7:00 PM - 8:00 PM

SPONSOR PRODUCT THEATER: EDGEWISE THERAPEUTICS

Details Coming Soon…

7:00 AM - 8:30 AM

EXHIBITS & BREAKFAST

7:15 AM - 8:15 AM

SPONSOR PRODUCT THEATER: BIOMARIN

Details Coming Soon…

-INTRODUCTION & GENETICS-

8:30 AM

Welcome

Martin S. Maron, MD & Steve R. Ommen, MD

8:35 AM

HCM At 65 Years: A Contemporary Treatable Disease. How Did This Happen?

Barry J. Maron, MD

8:55 AM

How Common is HCM Really?

Daniele Massera, MD, MSc

9:10 AM

The Max Saines Lecture: Familial & Nonfamilial Inheritance: Is HCM Always Genetic?

Jodie Ingles, MPH, PhD

9:35 AM

Why Should I Get Genetic Testing on My HCM Patient?

Anjali T. Owens, MD

9:55 AM

BREAK

10:10 AM

Gene (+) / Phenotype (-): Is There Anything to Do (Yet)?

Michelle Michels, MD, PhD

10:30 AM

Novel Views on HCM Screening from a Pediatric Perspective

Seema Mital, MD, FRCP

10:50 AM

Panel Discussion: Prevalence, Genetics, Screening

Drs. Massera, Ingels, Owens, Michels, Mital

Steve R. Ommen, MD (Moderator)

-IMAGING-

11:15 AM

Cardiac Magnetic Resonance In HCM: LGE, ESV & What the HCMR Registry May Tell Us

Milind Desai, MD, MBA

11:35 AM

Integrating Echocardiography & Multimodality Imaging To Improve Contemporary HCM Care

Harry Rakowski, MD, FRCPC

12:00 PM

LUNCH

12:05 PM

SPONSOR PRODUCT THEATER: BRISTOL MYERS SQUIBB

Details Coming Soon…

1:10 PM

Improving Diagnosis & Beyond In HCM: Will Artificial Intelligence Be the Answer?

Konstantinos Siontis, MD

1:30 PM

Panel Discussion: Modern Imaging & Management of HCM

Drs. Desai, Rakowski, Siontis

Martin S. Maron, MD (Moderator)

1:55 PM

BREAK

-PREVENTION OF SUDDEN DEATH-

2:10 PM

Risk Stratification To Save Lives: Selection Of Patients for ICD

Martin S. Maron, MD

2:35 PM

Unique Challenges in Sudden Death Prevention in Young HCM Patients: Aren’t Kids Just Small Adults?

Gabrielle Norrish, BMBCh, PhD

3:00 PM

Selection of Devices to Prevent Sudden Death: Sub-Q v. Transvenous ICD?

Danna A. Spears, MD

3:20 PM

Panel Discussion: Risk Stratification

Drs. Maron, Norrish, Spears, Michels

Barry J. Maron, MD (Moderator)

3:45 PM

Differential Diagnosis: Diseases That Look Like HCM But Are Not: Identification & Precision Medicine Strategies

Danon Disease - Barry Greenberg, MD

Cardiac Amyloidosis - Mat Maurer, MD

Fabry Disease - Albree Tower-Rader, MD

4:45 PM

ADJOURN

5:00 PM

SPONSOR PRODUCT THEATER: SANOFI

Details Coming Soon…

6:30 PM

RECEPTION

Cocktails/Hors d’oeuvres for Registrants & Faculty

Join us in the Lighthouse Ballroom for networking alongside faculty & fellow attendees, set against the backdrop of Boston Harbor & the city skyline.

Sponsored by Cytokinetics

7:00 AM - 8:30 AM

EXHIBITS & BREAKFAST

7:15 AM - 8:15 AM

SPONSOR PRODUCT THEATER: ZIO BY IRHYTHM

Details Coming Soon…

-HEART FAILURE IN OBSTRUCTIVE HCM-

8:30 AM

Obstructive HCM: Recognition, Mechanism, Natural History

Steve R. Ommen, MD

8:55 AM

Traditional Medical Therapies with Beta-Blocker/Calcium Channel Blockers (and Don’t Forget about Disopyramide)

Mark V. Sherrid, MD

9:15 AM

From Bench to Bedside: The Incredible Story Behind the Development of Myosin Inhibitors

Fady I. Malik, MD, PhD

9:35 AM

BREAK

9:50 AM

First Generation Cardiac Myosin Inhibitor: What Have We Learned & Where Are We Going?

Iacopo Olivotto, MD

10:15 AM

Next Generation Myosin Inhibitor: What Can We Expect?

Martin S. Maron, MD

10:40 AM

What Is the Evidence for Cardiac Remodeling with Myosin Inhibitors…And Is It Different Than with Septal Reduction Therapies?

Andrew Wang, MD

11:00 AM

Integrating Myosin Inhibitors into Busy Cardiovascular Practices: Practical Insights

Theodore Abraham, MD

11:15 AM

Panel Discussion: Deeper Dive into Novel Drug Therapy

Drs. Sherrid, Olivotto, Maron, Wang, Abraham

Steve R. Ommen, MD (Moderator)

11:40 AM

LUNCH

11:45 AM

SPONSOR PRODUCT THEATER: CYTOKINETICS

Details Coming Soon…

12:50 PM

The Doug Wigle Lecture: Surgical Septal Myectomy: The Gold Standard. Should We Be Operating Earlier?

Joseph Dearani, MD

1:15 PM

Operating on Obstructive HCM with Mild Septal Hypertrophy: Expanding the Myectomy Spectrum

Prem Shekar, MD

1:35 PM

How Do We Develop More Great Myectomy Surgeons?

Eduard Quintana, MD, PhD

1:55 PM

Alcohol Septal Ablation: 30 Years Later

Rick A. Nishimura, MD

2:15 PM

Future of Catheter-Based Therapies for Obstructive HCM

Carey Kimmelstiel, MD

2:35 PM

Contemporary Management of Obstructive HCM: Putting It All Together in the Era of Novel Drug Therapies

Steve R. Ommen, MD

3:05 PM

BREAK

-HEART FAILURE IN NON-OBSTRUCTIVE HCM-

3:20 PM

Non-Obstructive HCM: Recognition, Mechanism, Natural History & Mortality

Ethan J. Rowin, MD

3:45 PM

Current Management of End-Stage Heart Failure with or without Systolic Dysfunction: Drugs, Devices & Who Should Be Listed for Heart Transplant?

Michelle Kittleson, MD, PhD

4:10 PM

Is More Help on The Way? Future Medical Therapies for Nonobstructive HCM

Ahmad Masri, MD, MS

4:35 PM

Atrial Fibrillation: Unique Perspectives on Management

Ethan J. Rowin, MD

4:55 PM

ADJOURN

5:15 PM

SPONSOR PRODUCT THEATER: VIZ.AI

Details Coming Soon…

6:30 PM

RECEPTION: HCMA Patient Perspective & Voice

Cocktails/Light Dinner for All Registrants

Join us in the Lighthouse Ballroom for special programming from the HCMA alongside fellow attendees.

Hosted by The HCMA & Lisa Salberg

7:00 AM - 8:15 AM

EXHIBITS & BREAKFAST

7:00 AM - 8:00 AM

SPONSOR PRODUCT THEATER: TENAYA THERAPEUTICS

Details Coming Soon…

-ELEVATING HCM CARE-

8:15 AM

Different Outcomes by Race?: Improving HCM Care for Minorities

Melissa S. Burroughs, MD, MS

8:25 AM

Delivering Optimal Care in HCM: The Role of Advanced Practitioners

Deatrah DuBose, ACNP, BC

-THE FUTURE OF CLINICAL TRIALS IN HCM-

8:35 AM

The Enormous Challenge Of End Points: Will New HCM Therapies Live or Die by This Issue?

James Udelson, MD

8:50 AM

How Exactly Are Drugs Approved? Drug Approval In Rare Diseases: The View of the FDA

Rosalyn Adigun, MD

9:05 AM

Panel Discussion: HCM Clinical Trial Design

Drs. Burroughs, Udelson, Adigun; Ms. Salberg

Steve R. Ommen, MD (Moderator)

-EXERCISE IN ATHLETES-

9:20 AM

Exercise In HCM: What Should We Be Telling Patients?

Rachel Lampert, MD

9:30 AM

Exercise in HCM: Why Don’t We Just Let Them All Play?

Matthew W. Martinez, MD

9:40 AM

Decision-Making For Sports Eligibility in HCM: Efforts To Keep the Patients & Athletic Field Safe

Barry J. Maron, MD

9:50 AM

Panel Discussion: Exercise in HCM

Drs. Lampert, Martinez, Maron

Martin S. Maron, MD (Moderator)

10:15 AM

BREAK

-GLOBAL EXPERIENCE OF HCM-

10:30 AM

Myectomy in a War Zone: The Ukrainian Surgical Experience

Kostiantyn Rudenko, MD, PhD

10:45 AM

China: Global Expanse of HCM & Myectomy

Shuiyun Wang, MD

11:00 AM

Decoding 500 Years of HCM: What Iceland Has Taught Us & What More We May Learn

Berglind Adalsteinsdottir, MD, PhD

11:15 AM

India: Trials & Tribulations of Growing an HCM Center In the World’s Most Populous Country

Hisham Ahamed, MD, DM

11:30 AM

The 50-Year Tuscany Cohort: An Italian HCM Renaissance

Franco Cecchi, MD

11:45 AM

HCM in Africa

Ntobeko Ntusi, MD, MBChB

-GENE THERAPY: IS IT FINALLY HERE?-

12:00 PM

Gene Therapy: Editing, Precision, Personalized Medicine…What Does It All Mean for HCM & Why?

Eric D. Adler, MD

12:20 PM

Status of Gene Therapy Clinical Trials In HCM & What To Expect Moving Forward

Louisa Mestroni, MD, FACC

12:40 PM

EPILOGUE: What the Past May Teach Us About The Future

Martin S. Maron, MD

12:45 PM

ADJOURN